Laxity lacks the expected or desirable firmness.
From the Latin laxus , lax is an adjective that refers to something relaxed, free or that does not have the tension that, by nature, it should have . The term can be used in reference to something physical or symbolic.
For example: “I like looser fabrics, which do not fit the body so much” , “He was always a man of loose beliefs, capable of contradicting himself with great naturalness” , “A loose tablecloth that does not conform to the table is the best decorative option for the banquet” , “You cannot be lax in complying with the rules” .
Loose connective tissue is known as the type of tissue in the body that has a low percentage of fibers and whose origin is found in the mechymal tissue . Loose connective tissue can be divided into mucosal connective tissue or reticular connective tissue , among other subtypes.
Lax complexion
Cutis lax , on the other hand, is a rare disease that involves the degeneration of the skin 's elastic fibers. It is caused by a defect in the enzyme lysyl oxidase that causes the skin to become loose and appear to hang from the body.
Most cases of cutis laxo are inherited in an autosomal recessive, dominant, or X-linked recessive manner, although there are reports of acquired cases. Given the histological abnormalities in the structure or quantity of elastin that occur in almost all cases of cutis laxo, research studies have focused on genetic mutations that lead to alterations in the processing of elastin in the extracellular matrix or in the structure.
Something loose is indefinite or imprecise.
ADCL
Symptoms of autosomal dominant cutis laxus (ADCL) can appear at any point in a person's development between birth and early adulthood.
In some cases, only the symptom of lax skin is seen. However, defects in the eyes and nose, as well as lung (pulmonary emphysema) and vascular (aortic aneurysms) problems are seen in certain families. It is advisable to perform lung function tests and an echocardiography to prevent the disorders just mentioned, since they can put the patient's life at risk.
Autosomal recessive cutis laxo
ARCL is found in various subtypes, depending on the symptoms of each case and the gene causing the disease; Basically, three types can be recognized, and the first two are also divided into more than one subtype. Let's see the main characteristics of some of them:
ARCL1A
* lax skin, lung problems such as emphysema (during the first years of life) and hernias;
* the age at which these symptoms appear varies greatly, even within a family;
* is due to mutations in the FBLN5 gene.
ARCL2A
* wrinkled skin all over the body (age usually causes this to improve);
* congenital hip dislocation, myopia, hernias and elongated anterior fontanelle;
* many cases present a significant delay in psychomotor development, as well as epileptic seizures ;
* It is caused by mutations in the ATP6V0A2 gene.
ARCL3
* growth and mental retardation (of varying intensity);
* cataracts, lax joints;
* appearance of excessive aging;
* pulmonary and cardiovascular disorders are not common.
symbolic use of the notion
In a symbolic sense, laxity is associated with vagueness , impression or indefiniteness .
If a person states that they have a “loose relationship” with their romantic partner, they will be indicating that the degree of commitment is not very strong. Likewise, a president who provides “loose support” to a minister will be giving him support that may be considered weak or that lends itself to misunderstandings and misrepresentations.